为把 S-2-anilino-methylpyrrolidine 用作 chiral 的 -aminoalkylphosphonic 酸的不对称的合成的一个改进过程辅助被描述。涉及这个协议的化学转变能在温和反应状况下面继续提供好化学药品, enantiomeric 让步。
An improved procedure for the asymmetric synthesis of α-aminoalkylphosphonic acids using S-2-anilinomethylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric yields.