中文摘要：

本文简述阿尔兹海默病（AD）的研究概况及表观遗传学的研究内容,以Aβ假说为中心展开对AD表观遗传机制研究进行探讨,为认识AD的发病机制提供理论依据.

英文摘要：

This paper briefly introduces the research situation of Alzheimer′s disease （AD） and the contents of epigenetics, as well as discusses the research of AD epigenetic mechanism based on Aβ hypothesis for the center,providing theoretical basis for understanding the pathogenesis of AD.