目的探讨强脉冲光(IPL)治疗长期外用激素制剂所致面部激素依赖性皮炎的有效性和安全性。方法治疗组患者应用强脉冲光照射,每3周治疗1次,5次为1个疗程。治疗参数选择从低能量开始,一般20—25J/cm^2。对照组应用蓝科肤宁冷湿敷(1—2次/d)联合氯雷他定口服(10mg,1次/d,4周为一个疗程)。两组均于1疗程结束后判定疗效。结果两组主观症状(灼热、瘙痒、疼痛、干燥感、紧绷感)疗效比较,治疗组有效率78.38%,对照组为83.33%,两组差异无显著性(P〉0.05)。两组客观体征(毛细血管扩张、痤疮样皮炎、色素沉着、皮肤老化、毳毛)疗效比较,治疗组有效率86.49%,对照组有效率38.10%,治疗组显著优于对照组(P〈0.01)。结论IPL治疗长期外用激素制剂所致面部激素依赖性皮炎安全、有效。
Objective To evaluate the therapeutic effect and safety of intense pulsed light in treatment of facial sensibility dermatitis with hormone preparation for long time application. Method In treatment group IPL was applied on face with an interval of 3 weeks, five sessions of treatment served as a course, and the therapeutic parameter was selected in low-grade power about 20 -25J/cm^2 at the start. In the control group lankefuning was applied by cold compress on face 1- 2 times daily,with loratadine taken orally 10mg, 1 times daily, 4 weeks as a therapeutic course. Result Total effective ratio of rational symptom( ealoreseence, pruritus, pain, aridity, tautness)in treatment and control group were 78.38%, 83.33% respectively, there was no statistical difference between them( P 〉 0.05 ). And total effective ratio of objective sign( telangiectasis, aene, pigmentation, skin aging,wolly hair)in treatment and control group were 86.49%, 38.10% respectively. Treatment group has significant effect compared with control group ( P 〈 0.01 ). Conclusion Intense pulsed light is safe, effective method in the treatment of facial sensibility dermatitis with hormone.