中文摘要：

随着后基因组时代的到来，药物发现研究领域不断涌现出一系列新思路、新技术、新方法，从而迅速推进药物发现的多元化发展。一方面，基因组学、蛋白质组学、转录组学、代谢组学、生物信息学、系统生物学等新兴学科的崛起与发展，为药物发现提供更为广泛而深刻的理论基础；另一方面，计算机辅助药物设计、高通量筛选、高内涵筛选、生物芯片、转基因和RNA干扰等高新技术的发展和完善，为药物发现提供了新的技术手段和有力工具，极大地拓宽了药物发现的途径。本文结合近年来现代生物学的研究进展，综述现代生物学对药物发现过程的影响。

英文摘要：

Drug discovery has been improved greatly by series of new ideas and new technologies as well as new approaches emerging in the postgenomic era. On the one hand, the theoretics of drug discovery ve and more profound as the development of numerous new disciplines such as genomics, proteomics, transcriptomics, metabonomics, bioinformatics and system biology; on the other hand, the pathways for new drug discovery are broadened by the continuous improvement of technological platforms including computer-aided drug design, high throughput screening, high content screening, biochip, transgenic and RNAi technology. Based on the recent advances on the modern biology, in this article, we specially reviewed the impacts of modern biology on the process of drug discovery.