目的观察前列安栓对精液不液化患者的治疗效果及其对精子浓度和前向运动精子的影响。方法将120例精液不液化患者随机分为治疗组80例,对照组40例,分别予前列安栓纳肛(1粒,每日1次,睡前纳肛)和维生素E胶囊口服(100mg,1次·d^-1,口服),连续治疗12周为1个疗程,记录精液液化情况及精子浓度和前向运动精子百分率。结果1个疗程后,治疗组痊愈62例(81.58%),有效8例(10.53%),无效6例(7.89%),总有效率为92.11%。对照组痊愈6例(16.22%),有效7例(18.92%),无效24例(64.86%),总有效率为35.14%。治疗组总有效率明显优于对照组(P〈0.01)。同时,前列安栓可以显著提高精子活力,与对照组比较,差异有统计学意义(P〈0.01)。结论前列安栓可显著缩短精液液化时间,同时可提高精子活动力,值得在临床中推广。
Objective To observe the therapeutic effect of Qianliean Suppositories in the patients of non - liquefied semen and the impacts on sperm concentration and forward movement sperm. Methods One hundred and twenty patients of non- liquefied semen were randomized into a treatment group( 80 cases)and a control group (40 cases). Separately, Qianliean Suppositories ( 1 rectal suppository, once a day, before sleep) and Vitamin E Capsules (100rag, once a day,oral administration)were given. Continuous treatments of 12 weeks made 1 session. The semen liquefaction, sperm concentration and forward movement sperm percent- age were recorded. Results After 1 session treatment, in the treatment group, 68 cases (81.58%)were cured,9 cases( 10.53% )effective and 6 cases (7.89%)failed. The total effective rate was 92.11%. In the control group ,6 cases( 16.22% )were cured ,7 cases ( 18.92% )effective and 24 (64.86%)failed. The total effective rate was 35.14%. The total effective rate in the treatment group was obviously superior to the control group(P 〈 0.01 ). Qianliean Suppositories could improve significantly sperm activity as compared with the re- sult in the control group, indicating the significant difference(P 〈 0.01 ). Conclusion Qianliean Supposito- ries significantly shortens the time of semen liquefaction and improves sperm activity. Hence, this therapy de- serves to be promoted in clinical practice.