压力性尿失禁是一种常见的、遗传的和多向的下尿路障碍,是医学研究的国际热点。基因型和表现型之间的关系是复杂的,而且易受环境影响。基因的变异会增加压力性尿失禁的患病风险,如胶原蛋白I A 1、5-羟色胺2A等基因的多态性。但相关基因的研究并不多,不够深入,本文就目前已有研究做一个综述。
Stress urinary incontinence is a common ,genetic and multidirectional urinary disorder ,a hot spot in medical research international.The relationship between genotype and phenotype is complex ,and vulnerable to environmental impact.Gene mutations can increase the risk of SUI ,such as collagen IA1, 5-serotonin 2A gene polymorphism.But related gene research is neither much nor enough in-depth,this article will do a review on current research.