中文摘要：

Kolliker器是哺乳动物耳蜗发育过程中的一种暂态结构,存在于胚胎中晚期和出生后早期,是耳蜗不成熟的标志之一.虽然Kolliker器在对外界声音敏感后退化,但其可能在激发耳蜗产生不依赖外界声音的自发性活动,促进感觉细胞和听觉神经元的存活和成熟,以及突触的发育和音频定位的精细化中发挥重要作用.

英文摘要：

Kolliker＇s organ,which is a transient structure of cochlea during development,in late embryonic and early postnatal period,is one of the signs of cochlear immaturity.Kolliker＇s organ degradates after the sensory structures become sensitive to external sound.The putative role of Kolliker＇s organ is important for generating the intrinsic spontaneous activity whichpromotes the development and maturation of a fully functional auditory system.