中文摘要：

通过测定鹿特异性复合麻醉剂麻醉下大鼠大脑皮层Na^＋-K^＋-ATP酶活性的变化,探讨了其麻醉与大鼠大脑皮层Na^＋-K^＋-ATP酶的关系。将32只纯种SD大鼠随机分成对照组、诱导组、麻醉组和催醒组,对照组大鼠按30 m L/kg体重腹腔注射生理盐水,其余各组按30 mg/kg体重腹腔注射鹿特异性复合麻醉剂,于各时间点冰上采集各组大鼠大脑皮层,采用比色法测定其Na^＋-K^＋-ATP酶活性。结果显示,药物作用后大鼠大脑皮层Na^＋-K^＋-ATP酶活性显著低于对照组（P〈0.05或P〈0.01）。该结果提示大鼠大脑皮层Na^＋-K^＋-ATP酶活性变化与鹿特异性复合麻醉剂的麻醉作用具有相关性。

英文摘要：

This experiment was aimed to determine the activity of Na^＋-K^＋-ATPase in rats＇ cerebral cortex region and investigate the relationship between specificity anesthetic for deer and Na^＋-K^＋-ATPase in cerebral cortex. 32 SD rats were randomly divided into control group, induction group, anesthesia group and the wake group. Rats of the control were injected with saline（30 m L / kg）,rats of the other group were injected with drug（30 mg / kg）. The samples of cerebral cortex in different period were separated and the activities of Na^＋-K^＋-ATPase were determined by using colorimetry methods. The results showed that the activities of Na^＋-K^＋-ATPase in cerebral cortex after administration were decreased obviously compared with that in the control group（P〈0.05 or P〈0.01）. It indicated that the changes of the activity of Na^＋-K^＋-ATPase in the cerebral cortex were correlated with the specificity anesthetic for deer.