中文摘要：

随着1,3-二炔类化合物在有机合成及功能材料等领域的广泛应用,它的合成引起了广大研究者的关注。本文阐述了1,3-二炔类化合物的合成发展历史,着重综述了近十年来1,3-二炔类化合物的合成发展情况,按原料类别进行介绍,主要包括以末端炔、炔基卤化物、金属炔化物和烯基卤化物等为原料合成1,3-二炔化合物的新成果。文章还分析了一些合成方法在医药领域的应用和重要的反应机理,并总结了该类化合物的合成及未来发展方向。

英文摘要：

Much attention has been paid to the synthesis of 1,3-diynes with the development of its wide applications in the fields of organic synthesis and functional materials.This review describes the synthesis history of the 1,3-diynes and emphatically the synthesis development of 1,3-diynes in recent 10 years.It introduces the new achievements in synthesis of 1,3-diynes from its starting materials including terminal alkynes,alkynyl halides,metal acetylides,alkenyl halides,and other precursors.Medical applications of some reactions and relevant mechanisms are also described in this paper.Finally,the synthesis of 1,3-diynes is concluded and the development trends in the field of 1,3-diynes synthesis are proposed.