中文摘要：

本文结合作者的临床与研究工作，对先天性中外耳畸形的流行病学、胚胎发育、发病机制、临床表现及防治做了总结，并介绍了一些作者的工作，包括先天性中外耳畸形患者的标准化诊治流程和个性化序列治疗方案的选择、手术方法与器械的创新和改进，以及耳胚胎学研究和基于胚胎研究的临床基因筛查，期望为此类患者的诊治提供参考。

英文摘要：

In this paper the author,combining with her own work and clinical experience, makes a summary of the epi？demiology, embryonic development, pathogenesis, clinical symptoms and signs, treatment and prevention about congenital de？formation of the middle and outer ears, and introduces some of her work, including the standardized process and principle for selecting individualized sequence project, innovation and improvement of surgical instruments and operation methods, estab？lishment of ear embryonic research and gene screening of clinical patients based on the embryonic research, expecting to pro？vide references of diagnosis and treatment for these kinds of patients.