中文摘要：

目的探讨灯盏细辛注射液临床使用合理性与安全性再评价问题。方法采取分层随机法抽取某医院2013年1至12月份使用灯盏细辛注射液住院病历120份,通过药品说明书推荐及药物利用研究,探讨灯盏细辛注射剂临床使用合理性与安全性再评价研究模式。结果该医院2013年灯盏细辛注射液临床使用中医辨病（34.17%）、中医辨证（18.33%）、溶媒剂量（35.83%）及给药浓度（2.50%）合理性百分率普遍偏低,8,7,6项指标合理性总得分百分率平均值亦不高（53.96%,56.55%,49.31%）,尤其超浓度使用情况严重（a DDCs=28.09,c DUI=2.93〉1）。结论应加强灯盏细辛注射液临床监测工作。

英文摘要：

Objective To explore the method of research on the rationality and safety of traditional Chinese medicine injections （TCMIs） in clinical use, such as Dengzhanxixin injections. Methods In this study, 120 medical records from the certain hospital, which contained Dengzhanxixin injections prescription during 2013, were selected randomly and evaluated by instructions recommendation and drug utilization research （DUR）. Results There were poor rationality and safety, such as in disease and syndrome differentiation of traditional Chinese medicine （34. 17% and 18.33% for rationality, respectively）, the solvent volume （35.83% for rationality） , the administration concentration （2. 50% for rationality） of Dengzhanxixin injections. The six or seven or eight parameters total scores were 53.96% , 56.55% , 49.31% for rationality, respectively and there was superconcentration administration （average defined daily concentration 28.09 and drug utilization index 2.93 ）. Conclusion In brief, it should strengthen to monitor Dengzhanxixin injections in clinical use.