中文摘要：

抗菌肽（AMPs）是一类广泛存在于自然界生物体中的小肽类物质,它是机体先天性免疫系统的重要组成部分。AMPs作为传统抗生素的替代品被广泛重视,然而细菌对于AMPs的抗性如同对抗生素的耐药性一样不容忽视。本文主要从浮游菌、生物膜和信号调节3个方面阐述细菌对于AMPs的抗性及机理。

英文摘要：

Antimicrobial peptides （ AMPs）, are a class of small peptides that widely exist in many creatures in nature, and they are essential components of the innate immune system. AMPs, as a potential alternative to the traditional antibiotics, gain more extensive attention ; however, the resistance of bacteria to AMPs as well as to antibiotics should not be ignored. This review summarized the resistance of bacteria to AMPs and it＇ s mechanism from three aspects of planktonic bacteria, biofilm and signal regulatory.