本文简要介绍了用于活体分子影像的各种合成探针。探针是分子影像的重要因素。诸如放射性标记化合物、小分子荧光染料等基于小分子化合物的探针,金属纳米粒子、荧光量子点、磁性纳米材料、稀土发光纳米材料、氧化物纳米材料、碳纳米材料等基于无机纳米材料的探针,枝状聚合物、胶束和囊泡、脂质体及其类似物等基于合成软物质纳米材料的探针均在分子影像领域被广泛应用。
Synthetic probes for in vivo molecular imaging are introduced in this paper. Probes are an important part of imaging. Small molecule compound based probes like radio-labeled compounds, small molecular fluorescence dyes, inorganic nano-material based probes like metal nano-particles, fluorescent quantum dots, magnetic nano-materials, rare earth light emitting nanomaterials, metal oxide nanomaterials, carbon nanomaterials and synthetic soft matter nanomaterial based probes of dendrimers, micelles and vesicles, liposomes and analogs have all been widely used in molecular imaging.