欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
目的：观察17aα-D-高炔雌二醇-3-乙酯及其联合化疗对EC901食管癌的抑制作用。方法：将接种EC901瘤细胞的裸鼠分为对照组、17aα-D-高炔雌二醇-3-乙酯组、5-氟尿嘧啶（5-Fu）组、17aα-D-高炔雌二醇-3-乙酯联合5-Fu组,连续给药9d,分别检测肿瘤抑制率、外周血常规、骨髓有核细胞计数、肿瘤病理等指标。结果：17aα-D-高炔雌二醇-3-乙酯治疗组瘤重明显小于对照组,联合5-Fu组肿瘤生长分别低于5-Fu组和照射组。结论：17aα-D-高炔雌二醇-3-乙酯联合5-Fu对EC901食管癌的抑制具有增效作用。
英文摘要：
Objective：To observe the inhibition effects of 17aα-D-homo-ethynylestradiol-3-acetate and combination with chemotherapy on esophageal carcinoma EC901.Methods：Inoculate the nude mice with esophageal cancer cells EC901 and then divided them into four treatment groups：17aα-D-homo-ethynylestradiol-3-acetate,5-Fu,17aα-D-homo-ethynylestradiol-3-acetate combined with 5-Fu and control group.Each group were continuous deliveried drugs for 9 days.After days,the inhibition rate of tumor,blood count,nucleated cell in bone marrow were examined.Results：Tumors of 17aα-D-homo-ethynylestradiol-3-acetate group were apparently lighter than control group.Compared with 17aα-D-homo-ethynylestradiol-3-acetate group and 5-Fu group,the growth of tumors in 17aα-D-homo-ethynylestradiol-3-acetate combined with 5-Fu group was slower.Conclusion：17aα-D-homo-ethynylestradiol-3-acetate combined with 5-Fu can increase the inhibition effects to EC901esophageal cancer.
同期刊论文项目
同项目期刊论文
Mitigating the Effects of Xuebijing Injection on Hematopoietic Cell Injury Induced by Total Body Irr
Mitigatingthe effects of Xuebijing injection on hematopoietic cell injury induced bytotal body irrad
Total body irradiationcauses long-term mouse BM injury via induction of HSC premature senescence ina
The Effects of p38 MAPK Inhibition Combined with G-CSF Administration onthe Hematoimmune System in M
Identification of hubgenes of pneumocyte senescence induced by thoracic irradiation using weightedge
Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in
期刊信息
位置：