Pellino1蛋白是近年来新发现的一种泛素连接酶,在固有免疫细胞和获得性免疫细胞中参与蛋白降解、蛋白间相互作用等,与炎症和自身免疫密切相关。本文就Pellino1蛋白的研究进展作一综述。
Pellinol protein is a ubiquitin ligase newly discovered in recent years. In the innate and acquired immune cells, Pellinol is involved in protein degradation, interaction between proteins and so on, which is closely associated with inflammation and autoimmunity. In this article, we have reviewed recent advance in the research of Pellinol ubiquitin ligase.