利用溶剂复合的方法制备了具有良好生物相容性的表面接枝聚(y-苄基-L-谷氨酸)的改性羟基磷灰石/聚乳酸纳米复合材料,并研究了其熔融与结晶行为.结果表明,聚乳酸的玻璃化转变温度为60.3℃,而复合材料的玻璃化转变温度达到65.8℃,不同样品在140℃等温结晶后,改性羟基磷灰石/聚乳酸复合材料的球晶直径仅为聚乳酸(PLLA)球晶直径的16.7%-66.7%.复合材料的熔点提高到184.4℃.
Biocompatible poly ( y-benzyl-L-glutamate ) modified hydroxyapatite/poly ( L-lactide ) ( PLLA ) nanocomosites were prepared via solvent-mixing method. Their melting and crystallization behavior were characterized by differential scanning calorimetry(DSC) and polarized optical microscopy(POM). The results show that the glass transition temperature of PLLA is 60. 3 ℃ and that of the composite can reach 65.8 ℃. After isothermally crystallized at 140 ℃, the spherulites diameter of modified HA/PLLA composites was only 16.7%-66. 7% compared with that of PLLA and the melting point of the composite can rise to 184.4 ℃.