中文摘要：

胚胎发育的分子机理是现今胚胎工程及发育生物学研究迫切需要了解的。由于胚胎发育的早期阶段就是胚胎干细胞阶段，因此两者在研究上有很好的重合性。通过对调节胚胎干细胞基因转录的三个具有代表性的转录因子Oct4、Sox2和Nanog的综述，展现出胚胎发育分子机理研究概况。

英文摘要：

Embryo development molecular mechanism is to need badly comprehended for some study domain, such as embryo engineering and development biology research. Because embryo development early stage is just to be ES stage, there is good coincidence on both research works. Recent advances in the studies of three typical tran-scription factors Oct4, Sox2 and Nanog contributing to pluripotency and self-renewal of ES cells by transcriptional regulations were simmanzed.