简要综述了近年国内外主要的可吸收止血材料,包括氧化纤维素与氧化再生纤维素、凝血酶制剂、纤维蛋白胶、胶原类制剂、止血明胶、α-氰基丙烯酸酯类组织胶、牛白蛋白和戊二醛化合物、壳聚糖类止血材料、微孔多聚糖类止血粉的组成、止血机制、安全性及临床应用,特别对不同成分的止血材料与机体凝血机制的关系进行总结,展望了可吸收止血材料未来的发展趋势。
This paper reviews the composition,mechanisms,safety and clinical application of major absorbable hemostatic materials,including oxidized cellulose,oxidized regenerated cellulose,thrombin sealants,fibrin glue,collagen,gelatin,α-cyanoacrylate sealants,bovine albumin and gluteraldehyde,chitosan-based hemostatic agents and microporous polysaccharide.Special attention was paid to the relationship between different absorbable hemostatic agents and the blood coagulation mechanism.We also discussed the future development of absorbable hemostatic agents.