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Conversion of N-Acyl-4-phenyl/benzyl-oxazolidine-2-thiones into Thiol Esters in the Presence of EtSH-K2CO3
  • ISSN号：1001-604X
  • 期刊名称：《中国化学：英文版》
  • 时间：0
  • 分类：O622.4[理学—有机化学;理学—化学]
  • 作者机构：[1]State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
  • 相关基金：Project supported by the National Natural Science Foundation of China （Nos. 20025207, 20272071, 20372075 and 20321202）, the Kn6wledge Innovation Project of the Chinese Academy of Sciences （No. KGCX2-SW-209）, and the Major State Basic Research Development Program （No. G2000077502）.
作者： HU, Qi SUN, Ya-Ping WU, Yi-Kang[1]
关键词： N-酰基-4-苯甲基-唑烷-2-硫因, 手性拆合, 丁间醇醛, 氨解作用, chiral auxiliary, cleavage, thiol ester, aldol
中文摘要：

N 酰 -- hydroxy-4-phenyl-oxazolidinethiones 能被处理很快在高收益变换成他们的乙醇 thiol 酉旨与在 0 è的 EtSH

英文摘要：

N-Acyl-β-hydroxy-4-phenyl-oxazolidinethiones could be rapidly converted into their ethyl thiol esters in high yields by treatment with EtSH at 0 ℃ in CH3CN or 9 ： 1 （V ： V） THF-H2O in the presence of a catalytic amount of K2CO3.

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期刊信息
  • 《中国化学：英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编：
  • 地址：上海市枫林路354号中科院上海有机化学研究所
  • 邮编：200032
  • 邮箱：
  • 电话：021-54925243
  • 国际标准刊号：ISSN：1001-604X
  • 国内统一刊号：ISSN：31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
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  • 被引量:175