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朊病毒病实验动物脑组织PrP^Sc样本库的建立
  • ISSN号：1003-9279
  • 期刊名称：《中华实验和临床病毒学杂志》
  • 时间：0
  • 分类：R512.62[医药卫生—临床医学;医药卫生—内科学]
  • 作者机构：[1]安徽理工大学医学院病原微生物学教研室,232001, [2]中国疾病预防控制中心病毒病预防控制所传染病预防控制国家重点实验室, [3]北京服装学院
  • 相关基金：国家自然科学基金委项目（No.30771914和30800975）;传染病重大专项（2009ZX10004-101,2008ZX10004-001,2008ZX10004-002）和卫生公益性行业（200802021）资助
作者： 张宝云[1], 田婵[1], 韩俊[1], 高晨[1], 石琦[1], 姜慧英[1], 周伟[1], 董小平[1]
关键词： 聚丙烯类, 腺病毒科, 实验室感染, Polypropylenes, Adenoviridae, Laboratory infection
中文摘要：

目的 研究新型离子型聚丙烯纤维以防止病毒感染.方法 构建四种离子型表面活性聚丙烯纤维,与表达GFP的重组腺病毒分别相互作用,通过观察GFP的表达和病毒六邻体壳粒基因的表达来判断纤维对病毒的吸附能力.结果 四种纤维对腺病毒具有一定的吸附或灭活能力.金属离子纤维和两性离子聚丙烯纤维具有更好的灭活病毒能力.结论 提示金属离子纤维和两性离子聚丙烯纤维可以作为实验室防护装备的原材料.

英文摘要：

Objective To provide better laboratory protection material in virology lab to prevent laboratory accident infection. Methods The four kinds of ionic polypropylene fibers were constructed and interact with recombinant adenovirus expressing GFP. Both the GFP expression and hexon gene expression of recombiant adenovirus were used to evaluate absorb ability of fibers. Results Both the amphoteric and iron ionic polypropylene fibers have certain adsorption or inactivated ability to virus in S min, the other two fibers decreased the growth within 20 min. Conclusion Both the amphoteric and iron ionic polypropylene fibers can be used as laboratory protection material in virology lab.

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期刊信息
  • 《中华实验和临床病毒学杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编：
  • 地址：北京市宣武区迎新街100号
  • 邮编：100052
  • 邮箱：
  • 电话：010-63530971
  • 国际标准刊号：ISSN：1003-9279
  • 国内统一刊号：ISSN：11-2866/R
  • 邮发代号:18-224
  • 获奖情况:
  • 中国科协优秀科技期刊二等奖,中华医学会优秀科技期刊二等奖,中国期刊方阵“双效”期刊
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,英国农业与生物科学研究中心文摘,荷兰文摘与引文数据库,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2000版）
  • 被引量:11623