中文摘要：

Rho相关的卷曲蛋白激酶（ROCK）是一种属于AGC家族的蛋白激酶，主要通过诱导应力纤维形成、重构细胞骨架等方式参与细胞收缩、迁徙、分裂、形态变化等生物学行为，对调节细胞的多种功能发挥重要的作用。

英文摘要：

Rho-associated coiled-coil protein kinase （ROCK） is a serine/ threonine kinase that be- longs to AGC family of kinases. By inducing the formation of stress fibers and reorganizing the cytoskeleton, it is involved in many biological behaviors of cells including cell contraction, cell migration, cell division, and morphological changes, and thus exerts important roles in regulating the multiple functions of cells.