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癫癎患儿共患注意缺陷多动障碍的临床分析
  • ISSN号:1008-8830
  • 期刊名称:《中国当代儿科杂志》
  • 时间:0
  • 分类:R749.17[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]北京大学第一医院儿科,北京100034
  • 相关基金:北京市自然科学基金(编号:7092105,7112131); 高等学校博士学科点专项科研基金(编号:200800011069,20090001110075); 卫生部临床学科重点项目基金(编号:2011-2013)
中文摘要:

目的评估癫癎患儿共患注意缺陷多动障碍(ADHD)的共患率,探讨引起癫癎患儿共患ADHD的相关危险因素。方法选取符合癫癎和癫癎综合征诊断标准、年龄在6~15岁的患儿256例,调查癫癎患儿与ADHD的共患率及危险因素。结果 192例患儿完成系统评定。ADHD的共患率为42.2%。首次发作年龄越早,抗癫癎药物治疗时程越长及多种抗癫癎药物联合应用者癫癎共患ADHD的共患率越高;Lennox-Gastaut综合征和全身强直-阵挛发作型癫癎及脑电图提示多病灶起源的癫癎患儿ADHD共患率较高。结论 ADHD在癫癎患儿中的共患率较高。癫癎患儿共患ADHD相关的危险因素包括:癫癎的首次发作年龄、癫癎发作类型、癫癎综合征的类型、脑电图特征及抗癫癎药物的使用。

英文摘要:

Objective To estimate the prevalence of attention deficit hyperactivity disorder(ADHD) in children with epilepsy,and the factors that may contribute to the prevanlence of co-morbidity between ADHD and epilepsy.Methods A total of 256 children aged 6-15 years old who were diagnosed with epilepsy were enrolled.The prevalence of ADHD in children with epilepsy,and the factors that may contribute to the development of co-morbidity between ADHD and epilepsy were explored.Results The systematic evaluation in 192 patients was completed.Of the 192 children,81(42.2%) were diagnosed with ADHD.The earlier the epilepsy onset,the higher the frequency of the co-morbidity of ADHD occurring.The longer the period of antiepileptic medication,the higher the prevalence of the co-morbidity of ADHD.Epileptic children receiving a combination of antiepileptic drugs had a higher prevalence of ADHD.ADHD was more common in children with some specific types of epilepsy,such as Lannox-Gastaut syndrome and generalized tonic-clonic epilepsy,or epilepsy with multifocal epileptic discharges in the EEG record.Conclusions ADHD occurs frequently in children with epilepsy.The factors associated with increased risk of ADHD include the onset age of epilepsy,the types of seizures or epileptic syndromes,the epileptiform EEG discharges,and the effects of antiepileptic drugs.

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期刊信息
  • 《中国当代儿科杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国教育部
  • 主办单位:中南大学
  • 主编:杨于嘉
  • 地址:湖南省长沙市湘雅路87号
  • 邮编:410008
  • 邮箱:ddek7402@163.com
  • 电话:0731-4327402
  • 国际标准刊号:ISSN:1008-8830
  • 国内统一刊号:ISSN:43-1301/R
  • 邮发代号:42-188
  • 获奖情况:
  • 中国科技论文统计源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:18305