中文摘要：

采用四步反应合成了一种新的具有良好生物相容性和生物降解性的末端带有磷酰胆碱（PC）基团的聚丁二酸丁二醇酯PBS-PC.采用1HNMR、IR、凝胶色谱（GPC）和X射线光电子能谱（XPS）表征了聚合物的结构.同时研究了聚合物的亲疏水性能、体外降解、溶胀率和对模型药物中性红的缓释性能.结果显示：PC基团引入,在一定程度上提高了PBS的亲水性、降解速率、溶胀率和对中性红的缓释性能.

英文摘要：

A new biodegradable and biocompatible polymer, phosphorylcholine functionalized poly（butylene succinate） （PBS-PC） was synthesized via a four-step synthetic strategy. The results of 1H NMR, IR, gel permeation chromatography （GPC） and X-ray photoelectron spectroscopy （XPS） measurements demonstrated a successful construction of PBS-PC. Dynamic contact angle, in vitro degradation, swelling behavior and drug release measurements revealed that the PBS-PC showed higher hydrophilicity, degradation, swelling and faster drug release rates by using neutral red as a model drug.