中文摘要：

为考察介孔纳米羟基磷灰石（MHA）/左旋聚乳酸（PLLA）复合材料的性能,以十六烷基三甲基溴化铵（CTAB）为模板合成MHA,采用溶液相分离结合粒子沥滤法制备了不同纳米粒子含量的MHA/PLLA多孔支架复合材料,考察了其抗压缩性能和淬断面微观结构。采用溶液浇注法制备了MHA/PLLA复合膜,并对其拉伸性能和拉伸断面微观结构进行了研究。FTIR、XRD、TEM和氮气吸附测试等结果显示：合成的MHA具有典型的晶体结构、介孔结构和较高的比表面积。力学测试结果显示：在发生10%压缩形变时,填料含量为1%、5%和10%的MHA/PLLA多孔支架复合材料的抗压缩强度随填料含量增加而提高,与相应含量的纳米羟基磷灰石（HA）/PLLA多孔支架复合材料相比,分别提高了约37.0%、67.7%和144.7%。在填料含量为5%和10%时,MHA/PLLA复合膜的拉伸强度较HA/PLLA复合膜分别提高约38.7%和46.1%,拉伸模量分别提高约35.4%和14.5%。而且MHA/PLLA复合膜具有更高的断裂伸长率,填料含量为1%、5%和10%时断裂伸长率分别较HA/PLLA复合膜提高约91.3%、79.7%和96.1%。FESEM结果显示：尤其当填料含量较高时,MHA/PLLA多孔支架复合材料或复合膜中填料粒子分布较HA/PLLA中均匀。结果表明：与HA/PLLA复合材料相比,随着MHA含量增加,MHA/PLLA复合材料具有更好的力学性能,MHA在PLLA基体中分布相对更均匀。

英文摘要：

To evaluate the properties of mesoporous nano hydroxyapatite（MHA）/poly（L-lactide）（PLLA）composites,MHA was synthesized with cetyltrimethylammonium bromide（CTAB）as template.MHA/PLLA porous scaffold composites with different contents of nano particles were prepared using solution phase separation and particle-leaching method,and the compressive property and micro-structure of quenching fracture cross-sections were evaluated.And then MHA/PLLA composite films were prepared using solvent casting method and the tensile property and micro-structure of tensile fracture cross-sections were evaluated.FTIR,XRD,TEM and N2 adsorption test results show that the prepared MHA has typical crystal structure,mesoporous structure and higher specific surface area.The mechanical test show that the MHA/PLLA porous scaffold composites with filler content of 1%,5%and10% exhibit increasing compressive strength under 10% compression deformation with the filler content increasing,and are 37.0%、67.7% and 144.7% higher than those of corresponding content of nano hydroxyapatite（HA）/PLLA porous scaffold composites,respectively.With the filler content of 5%and 10%,the tensile strength of MHA/PLLA composite films are 38.7% and 46.1% higher than those of HA/PLLA composite films,the strength modulus are 35.4% and 14.5% higher,respectively.And MHA/PLLA composite films possess higher elongation at break.With the filler content of 1%,5% and 10%,the elongation at break are 91.3%,79.7% and 96.1% higher than those of HA/PLLA composite films,respectively.FESEM photographs show that the distribution of filler particles in MHA/PLLA porous scaffold composites or composite films is more uniform than that in HA/PLLA when the filler content is higher.The results indicate that,compared with HA/PLLA composites,better mechanical property and more evenly MHA distribution in PLLA matrix are obtained as the increasing content of MHA.