中文摘要：

通过重金属暴露法，研究了不同质量浓度Cd2＋（0．005、0．025、0．05、0．1mg／L）在168h内对缢蛏消化腺和鳃组织谷胱甘肽硫转移酶（GST）、酸性磷酸酶（ACP）、碱性磷酸酶（AKP）活性的影响。结果显示，Cd2＋对两种组织GST活性均有激活作用，且高浓度比低浓度更易快速诱导其活性，但在暴露的后期（〉96h），两个较高浓度组（0．05、0．1mg／L）GST活性均出现下降；两种组织的ACP活性（鳃组织0．005mg／L组除外）在暴露的6h即被显著诱导，并表现出剂效关系，但高浓度组更快达到峰值后就持续下降，于暴露中后期（〉72h）被不同程度抑制；消化腺（0．005mg／L浓度组除外）和鳃AKP活性在暴露168h内均表现出“抑制一诱导一抑制”的规律，并且较高浓度组活性反而比低浓度组更易被激活，各组AKP活性被诱导达到最高值后就持续下降直至被再次抑制。Cd2＋在低浓度水平下即能引起缢蛏两种组织的GST、ACP、AKP活性变化，表明Cd2＋的胁迫可对缢蛏机体的解毒体系和新陈代谢产生影响。

英文摘要：

Effect of waterborne Cd2＋ at different concentrations （0.005mg/L, 0.025mg/ L, 0.05mg/L, and 0. ling/L） on activities of glutathione S-transferase （GST）, acid phospha- tase（ACP） and alkaline phosphatase （AKP） in digestive glands and gills of Sinonovacula con- stricta were studied. It was found that the GST activity in the two tissues was stimulated by Cd2＋during the exposure time in all treatments, however, those in higher-dose treatments （0.05 mg/L,0.1 mg/L） decreased with the prolonged exposure. The activation of ACP by Cd2＋ in the two tissues began at the 6h time-point, and the activity increased with the increasing concentration of Cd2＋. For ACP activity, the higher-dose group reached the peak value earlierthan the lower-dose group, and was inhibited after 72h. Except 0. 005mg/L dose-treatment in digestive glands, the AKP activities in the two tissues showed a＂decrease-increase-decrease＂ trend during the 168h exposure time in the experiment, and those in higher-dose treatments were stimulated earlier than those in lower ones. AKP activity in each treatment decreased con- stantly after reaching the peak value respectively. The fluctuations in GST, ACP, and AKP ac- tivities in the experiment indicated that exposure to lower concentrations of Cd2＋ could have af- fected the metabolism and detoxification system of the organism.