中文摘要：

利用水相法合成了L-半胱氨酸包覆的ZnS（L—Cys—ZnS）量子点，并通过原子力显微镜、X射线衍射、红外光谱、荧光光谱对其进行了表征．实验表明，牛血清白蛋白（BsA）的加入可以使L—Cys—ZnS量子点体系的荧光强度增强，且荧光强度变化和BSA的浓度呈现良好线性关系，基于此建立了一种荧光探针测定BSA的新方法，其线性范围是1．0×10^-8-1．0×10^10-7～mol／L，检出限为2．0×10^-10mol／L．该方法操作简便快速、灵敏度高、检出限低，有望用于实际分析．

英文摘要：

L- cysteine capped ZnS （ L- Cys-ZnS） quantum dots （QDs） were successfully prepared by wet chemical route, which were characterized by atomic force microscope （AFM）, X-ray diffraction（XRD）, infrared radiation （IR） and fluorescent spectrometry. Then these QDs were used as fluorescent probes to detect bovine serum albumin （BSA） based on its enhancement effect on fluorescence of L- Cys-ZnS. Under the optimal conditions, fluorescene enhancement intensity increased linearly with BSA concentration at the range of 1.0 ×10^-8 - 1.0×10^-7 mol/L with detection limit of 2.0×10^-10 mol/L. This method to detect BSA is simple and with high sensitivity and low limit detection, which is expected to be used for practical samples.