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鱼尾葵花粉过敏的变应性鼻炎患者中血清总IgE及特异性IgE结果的分析
  • ISSN号:1001-1781
  • 期刊名称:《临床耳鼻咽喉头颈外科杂志》
  • 时间:0
  • 分类:R765.21[医药卫生—耳鼻咽喉科;医药卫生—临床医学]
  • 作者机构:[1]海口市人民医院检验科,海口570208, [2]海口市人民医院耳鼻咽喉科
  • 相关基金:基金项目:国家自然基金地区科学基金资助项目(No:81160129)
中文摘要:

目的:探讨鱼尾葵花粉过敏的变应性鼻炎(AR)患者中血清总IgE、特异性IgE和变应原皮肤试验之间的关系。方法:选择429例对鱼尾葵花粉过敏的AR患者为实验组,243例健康体检者为对照组。实验组进行皮肤试验和特异性IgE水平检测,鱼尾葵花粉特异性IgE采用BSA—ELISA法;所有个体均检测血清总IgE水平。结果:实验组血清总IgE的阳性率明显高于对照组的阳性率(分别为66.2%和15.6%,P〈0.01);实验组皮肤试验与血清特异性IgE之间差异无统计学意义(x^2=0.7588,P〉0.05);实验组血清特异性IgE和总IgE之间差异有统计学意义(x^2=50.639,P〈0.01);海口长居患者与来海南旅游过客血清特异性IgE之间、总IgE之间差异均无统计学意义(P〉0.05)。结论:变应原皮肤试验与检测鱼尾葵花粉特异性IgE2种方法在诊断鱼尾葵花粉过敏的AR中有重要作用,检测血清总IgE对鱼尾葵花粉过敏的AR患者的诊断有参考价值,鱼尾葵花粉过敏的AR患者IgE的阳性率与接触时间之间的关系,有待进一步研究。

英文摘要:

Objective:Exploring the relationship between total and specific IgE in serum and allergen skin test of carvota mitis pollen-induced allergic rhinitis patients. Method.. Four hundred and twenty-nine carvota mitis pollen-induced allergic rhinitis patients and 243 healthy control subjects were recruited. The experimental group carried out skin tests, and pollen-specific IgE were also examined by BSA-ELISA method. Total IgE in serum of all of the subjects were determined by ELISA. Result:The positive rate of the total IgE level of the patients were much higher than those of the controls(66.2 % vs. 15.6 %, P〈0.01). No statistically significance was found between the positivity of skin test and serum specific IgE of the experimental group(x^2 = 0. 758 8,P〉0.05). The difference between serum-specific IgE and total IgE was statistically significant(x^2= 50. 639, P〈0.01). There was no statis- tical significance of specific IgE and the total IgE in serum between long term residents in Haikou and Hainan Tourisms (P〉0. 05). Conclusion:Allergen skin test and carvota mitis pollen-specific IgE are two effective methods for the diagnosis of carvota mitis pollen-induced allergic rhinitis. The detection of total IgE in serum of carvota mitis pollen-induced allergic rhinitis provides a reference value for diagnosis. The relationship between concentration of IgE in serum of the carvota mitis pollen-induced allergic rhinitis and allergen contact duration is waiting for further study.

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期刊信息
  • 《临床耳鼻咽喉头颈外科杂志》
  • 北大核心期刊(2011版)
  • 主管单位:中华人民共和国教育部
  • 主办单位:华中科技大学同济医学院附属协和医院
  • 主编:黄选兆 孔维佳
  • 地址:武汉解放大道1277号
  • 邮编:430022
  • 邮箱:lcebh@yahoo.com.cn
  • 电话:027-85726342-8818
  • 国际标准刊号:ISSN:1001-1781
  • 国内统一刊号:ISSN:42-1764/R
  • 邮发代号:38-146
  • 获奖情况:
  • 全国优秀科技期刊,中国科技论文统计源期刊,中文核心期刊,中国期刊方阵“双效”期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国生物医学检索系统,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:12291