代谢组学技术在方法上具有整体性、系统性及综合性的特点,恰与中医学理论中的整体观、运动观及辨证观相吻合。文章综述了代谢组学的研究概况,并针对强直性脊柱炎(AS)的诊疗现状,从多个角度论述了基于代谢组学技术研究AS诊疗的优势所在。通过代谢组学有望发现更多与AS诊疗相关的特异性生物标志物,有助于阐明其发病机制,研发更有效经济的防治药物,进而达到早期诊断和治疗的目的。
Metabonomics technology has the holistic, systematic and comprehensive characteristics, and so the idea coincides with the overall concept, motion concept, dialectical concept of Chinese medicine in line. In this paper, the progress of metabonomics research is reviewed, and the advantages in the diagnosis and treatment of ankylosing spondylitis based on metabonomics technology are discussed from many angles. There is great hope for finding more specific biological markers associated with ankylosing spondylitis treatment, elucidating the pathogenesis and developing more effective economic drug which could help reach the aims of early diagnosis and early treatment on AS.