中文摘要：

目的 研究慢性鼻-鼻窦炎（chronic rhinosinusitis,CRS）主观调查量表与CT评估之间的相关性.方法 收集121例CRS患者的鼻腔鼻窦结局测量20条（sino-nasal outcome test-20,SNOT-20）、医学结局研究简表36项（medical outcome study short-form 36 items,SF-36）、视觉模拟量表（visual analogue scale,VAS）以及Lund-Mackay CT评分数据.在总体未分组情况下,分别进行主观量表之间、Lund-Mackey CT评分与主观量表之间的相关性分析.再按照CRS伴或不伴鼻息肉、性别、病史、文化程度等因素分组后进行主观量表之间、Lund-Mackey CT评分与主观量表之间的相关性分析和组间比较.结果 在总体未分组情况下,SNOT-20与SF-36呈负相关（r=-0.561,P＜0.01）,SNOT-20与VAS呈正相关（r=0.743,P＜0.01）,SF-36与VAS呈负相关（r=-0.504,P＜0.01）,而Lund-Mackey CT评分与主观量表之间在统计学上无相关性（P＞0.05）.在分组情况下,仅有CRS伴鼻息肉组的主客观评估之间存在相关性：Lund-Mackey CT评分与SNOT-20呈正相关（r、0.318,P=0.005）;Lund-Mackey CT评分与SF-36呈负相关（r=-0.358,P=0.002）;Lund-Mackey CT评分与VAS评分呈正相关（r=0.358,P=0.002）.Lund-Mackay CT评分、SNOT-20以及VAS评分在CRS伴和不伴鼻息肉两组患者间差异有统计学意义（t值分别为3.249、-2.409、-2.957,P值均＜0.05）.结论 CRS患者以其自测为基础的主观调查量表之间有着较好的相关性,而Lund-Mackey CT评分与主观量表之间仅在CRS伴鼻息肉组有相关性,且相关系数较弱.CRS患者是否伴鼻息肉与生活质量的高低并无必然联系.

英文摘要：

Objective To investigate the relationship between the patient-based questionnaires and the computed tomography （CT） staging in patients with chronic rhinosinusitis （CRS）. Methods Quantitative data of 121 preoperative recruits with CRS were collected by using the Lund-Mackay CT staging system, a visual analogue scale （ VAS）, sino-nasal outcome test-20 （ SNOT-20）, and the medical outcome study short-form 36 items （SF-36）. The patients were classified into several subgroups according to whether CRS was associated with nasal polyps （NP） or not, sex, duration of disease, and educational background.Correlation between the patient-based questionnaires and the CT staging were analyzed in the total cohort patients and subgroups. Results In the total cohort patients, there were significant correlations between SNOT-20 and SF-36 （ r = -0. 561, P ＜ 0. 01 ）, SNOT-20 and VAS （ r = 0. 743, P ＜ 0. 0l ）, and SF-36 and VAS （ r = - 0. 504, P ＜ 0. 01 ）, however, the CT staging did not correlate with the patient-based questionnaires （P ＞ 0. 05 ）. Significant but weak correlations were found between the CT staging and the patient-based questionnaires in the C RS with NP subgroup （CT vs SNOT-20, r = 0. 318, P = 0. 005; CT vs SF-36, r = - 0. 358, P = 0. 002; CT vs VAS, r = 0. 358, P = 0. 002）. Compared between CRS with NP and without NP subgroup, there were statistic differences on the Lund-Mackay CT stage and the SNOT-20 and VAS scores （t value was 3.249, -2.409, -2.957, respectively, all P＜0.05）. Conclusions The patient-based questionnaires correlate well with each other, but CT staging correlated significantly but weakly with the patient-based questionnaires only in the CRS with NP subgroup. Nasal polyps do not appear to be responsible for the adverse effects of CRS on quality of life.