中文摘要：

摘要：以廉价的L-谷氨酸为初始原料，首先使用邻苯二甲酸酐保护其a位氨基并进行分子内羧基的环酐化反应，再通过氨基与酸酐的反应在γ位引入异丙胺，最后用水合肼脱除氨基保护得到目标产物L谷氨酰异丙胺。利用1H-核磁共振（1H—NMR）、傅里叶红外光谱（FT—IR）以及液相色谱一质谱（LC—MS）对最终产物进行了结构表征和纯度测定，并通过改变反应时间、温度以及反应物的投料摩尔比对其合成条件进行了初步的探索和优化。

英文摘要：

Using cheap L-glutamie acid as raw material, phthalie anhydride was employed to protect the a amino group of L-glutamie acid, and acetic anhydride was used to form the glutamie anhydride. Then, the glutamic anhydride was attacked by isopropylamine to open the ring. Finally, hydrazine hydrate was used to deprotect the phthaloyl, and isopropyl-L glutamine was obtained. The structure of product in each step was confirmed by 1H-NMR, FT-IR and LC-MS. The synthesis was optimized under different reaction temperature, time and reactant ratios.