Corresponding Author:. Yun-Fei Yuan, Department of HepatobUiary Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, G uangzhou, Guangdong 510060, P. R. China. Tel: +86-20-87343118; Fax: +86-20-87343118; Email: yuanyf@mail.sysu.edu.cn.