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应用事件相关电位技术考察正常人名词和动词的脑区分布特征
  • ISSN号:2095-4344
  • 期刊名称:《中国组织工程研究》
  • 时间:0
  • 分类:R318[医药卫生—生物医学工程;医药卫生—基础医学]
  • 作者机构:[1]江苏省语言科学与神经认知工程重点实验室,江苏省徐州市221116
  • 相关基金:国家社会科学基金重点项目(01AYY004)、江苏省“青蓝工程”(科技创新团队)资助项目(QL200618)和江苏省哲学社会科学十一五规划资助项目(06JSBYY006)、徐州师范大学人文社会科学研究基金项目(05XWB34).
中文摘要:

目的:应用事件相关电位技术考察正常人脑区名词和动词的分布特征. 方法:实验于2006-03在徐州师范大学完成.选择在校大学生16名作为受试者,男女各8名,年龄19~22岁,进行词语搭配判断实验.①刺激材料包括180个启动刺激(“一Q”和“不M”,Q为名量词,M为能愿动词),以及180个目标刺激(名词和动词).启动词和目标词构成4组不同搭配的短语,其中2组为正确搭配,另2组为错误搭配.②实验任务:要求被试判断启动词和目标词的搭配是否正确.刺激材料为随机编排,启动词和目标词的呈现时间均为200 ms,启动词和目标词之间的时间间隔为300 ms,相邻两个trail间的时间间隔为2 500 ms.③实验评估:采用Neuroscan Synamps 2记录脑电,并使用Neuroscan 4.3对采集的脑电进行离线分析处理.最后用两因素重复测量的方差分析法对数据进行分析. 结果:16名被试的实验数据均纳入统计分析.①反应时和正确率:两种正确搭配短语“一Q+名词”和“不M+动词”反应时比较差异显著[F(1,30)=5.475,P=0.026];而二者的正确率未见显著效应.②Nd400的平均幅值:在目标刺激呈现后350~750 ms,额区Nd400的类型主效应十分显著[F(1,15)=14.211,P=0.002],“不M+名词”-“不M+动词”差异波Nd400成分在额区显著.在目标刺激呈现后450~530 ms,后部脑区Nd400的类型主效应十分显著[F(1,15)=11.042,P=0.005],“一Q+动词”-“一Q+名词”差异波Nd400更负.③潜伏期:在后部脑区,两个差异波的Nd400在潜伏期上差异也十分显著[F(1,15)=29.512,P=0.000],差异波“一Q+动词”-“一Q+名词”所诱发的Nd400更加延迟.④脑区电压分析:在目标词呈现后400~600 ms,差异波“不M+名词”-“不M+动词”在额区的电压更负,而“一Q+动词”-“一Q+名词”则在中央顶区有更负的电压值. 结论:对于正常人而言,名词和动词具有不同的大?

英文摘要:

AIT: To investigate the representations of nouns and verbs in the brain areas processed using event-related potential technique. METHODS: The experiment was carded out in Xuzhou Normal University in March 2006. A total number of 16 undergraduate students of either gender, aged 19-22 years, participated in the experiment of word matching.①)The stimuli presented to subjects ware 180 priming words (‘yi Q’ and ‘bu M’, Q was noun quantifier and M was modal verb) and 180 target words [noun (N) and verb (V)] in total. There ware four possible types of combining a priming word and a target word, among which two types were syntactically legal while other two types were syntactically illegal.②All the subjects ware demanded to judge whether the word matching of the priming words and target words was correct. Stimuli were arranged at random. Both the priming words and target words were presented for 200 ms with a stimulus onset asynchrony of 300 ms, and the interstimulus interval between two neighboring trails was 2 500 ms. ③Event related potentials ware recorded by Neuroscan Synamps 2, and were analyzed with Neuroscan 4.3, which ware further analyzed using a repeated-measurement of analysis of variance. RESULTS: The data of 16 subjects ware all included for the statistical analysis. ①Reaction time and accuracy: A significant difference in reaction time was found between two types of matching ‘yi Q+N’ and ‘bu M+V’ [F(1. 30)=5.475, P =0.026] but no difference for accuracy. ②The mean amplitude of Nd400: In time window of 350-750 ms, the main effect of types of matching on Nd400 of frontal region was extremely significant [F(1, 15)=14.211, P =0.002]. The difference wave ‘bu M+N’-‘bu M+V’ elicited a significant Nd400. In time window of 450-530 ms, the extremely significant main effect on Nd400 was found in the posterior scalp region [F(1,15)=11.042, P =0.005]. The difference wave ‘yi Q+V’-‘y/Q+N’ elicited a larger Nd400. ③Latency: In

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期刊信息
  • 《中国组织工程研究》
  • 北大核心期刊(2014版)
  • 主管单位:中华人民共和国卫生和计划生育委员会
  • 主办单位:中国康复医学会 《中国组织工程研究》杂志社
  • 主编:唐佩福
  • 地址:沈阳浑南新区10002邮政信箱
  • 邮编:110180
  • 邮箱:crter3377@163.com
  • 电话:024-31416864
  • 国际标准刊号:ISSN:2095-4344
  • 国内统一刊号:ISSN:21-1581/R
  • 邮发代号:8-584
  • 获奖情况:
  • 2001“百种中国杰出学术期刊,卫生部首届医药卫生优秀获奖期刊,北方优秀期刊,辽宁省一级期刊,第三、四届沈阳市优秀期刊一等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,荷兰医学文摘,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2014版)
  • 被引量:16688