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中文摘要：
通过静电纺丝法制备出纳米羟基磷灰石/丝素蛋白/聚己内酯复合超细纤维,利用扫描电镜、红外光谱仪、X射线衍射仪对纳米羟基磷灰石/丝素蛋白/聚己内酯复合超细纤维形貌和结构进行表征,并进行了拉伸测试。结果表明,随着超细纤维中羟基磷灰石含量的增加,纤维的直径逐渐降低,纤维中聚己内酯的结晶逐渐变差。相比于丝素蛋白/聚己内酯超细纤维,含有质量比为30%羟基磷灰石的复合超细纤维仍具有较好的力学性能。体外小鼠成纤维细胞（L929）培养表明,纳米羟基磷灰石/丝素蛋白/聚己内酯复合超细纤维对细胞没有毒性。
英文摘要：
Ultrafine nano-hydroxyapatite（nHA）/silk fibroin（SF）/poly（ε-caprolactone）（PCL） composite fibers were prepared via electrospinning.Scanning electron microscopy（SEM）,attenuated total reflectance-Fourier transform infrared spectroscopy（ATR-FTIR） and X-ray diffraction（XRD） were used to characterize the electrospun ultrafine nHA/SF/PCL composite fibers.The mechanical properties of fibers were also tested.The results show that the diameter of the fibers decreases and the crystallinity of PCL in the fibers becomes poor with increasing nHA content in the fibers.Compared with SF/PCL fibers,the mechanical properties of ultrafine nHA/SF/PCL composite fibers are still well when the nHA mass ratio is 30% in the fibers.In vitro mouse fibroblast（L929） cell culture indicates that the ultrafine nHA/SF/PCL composite fibers are non-toxicity.
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