中文摘要：

目的研究鸦胆子Brucea javanica种子的化学成分。方法运用硅胶色谱、ODS、Sephadex LH-20等色谱方法进行分离纯化,结合高分辨质谱和核磁共振波谱分析鉴定化合物的结构。结果从鸦胆子种子90%乙醇提取物中分离得到5个苦木内酯类化合物,分别鉴定为鸦胆子内酯W（1）、yadanziolide A（2）、鸦胆子苦素D（3）、鸦胆子苦素E（4）、javanicolide A（5）。结论化合物1为未见文献报道的新化合物。

英文摘要：

Objective To investigate the chemical constituents from Bruceae Fructus（the seeds of Brucea javanica）. Methods These compounds were isolated by means of silica gel, ODS, Sephadex LH-20 column chromatographies. Their structures were identified by the methods of high resolution mass spectrometry（HRMS） and NMR spectroscopic analyses. Results Five quassinoids were isolated from 90% ethanol extract in Bruceae Fructus and identified as yadanziolide W（1）, yadanziolide A（2）, bruceine D（3）, bruceine E（4）, javanicolide A（5）, respectively. Conclusion Compound 1 is a new quassinoid which has not been reported in literature.