中文摘要：

目的探讨腹腔镜手术在横结肠癌治疗中的临床应用,评估其安全性和疗效。方法收集2012年7月-2015年1月本院普通外科收治的109例横结肠癌患者临床资料,所有患者均接受了手术切除,其中行腹腔镜辅助横结肠癌根治术（腹腔镜组）45例,开腹横结肠癌根治术（开腹组）64例。比较两组围术期指标及临床疗效。结果腹腔镜组手术时间明显长于开腹组（170.5 min vs 145 min,P〈0.001）;腹腔镜组术中出血量小于开腹组（80 ml vs 110 ml,P〈0.001）;腹腔镜组术后排气时间、进流食时间、住院天数均短于开腹组（P均〈0.05）;两组清扫淋巴结个数、术后并发症发生率差异无统计学意义。两组3年总生存率和无病生存率差异无统计学意义。结论腹腔镜手术在横结肠癌治疗中与开腹手术相比,具有术中出血少、术后恢复快等优点,术后并发症发生率和远期生存率与开腹手术无显著差异。

英文摘要：

Objective To investigate the clinical efficacy of laparoscopic radical colectomy for transverse colon cancer and evaluate its safety and feasibility.Methods From July 2012 to January 2015,109 patients underwent laparoscopic or open radical colectomy for transverse colon cancer in the Department of General Surgery of Chinese PLA General Hospital.Forty-five patients underwent laparoscopic surgery and 64 patients underwent open surgery.Perioperative indicators and clinical efficacy were compared between two groups.Results The operating time was significantly longer in the laparoscopic group compared with open group（170.5 min vs145 min,P〈0.001）.The blood loss during the operation was lower in the laparoscopic group（80 ml vs 110 ml,P〈0.05）.Regarding postoperative outcomes,time to first oral intake,time to bowel function recovery,and the postoperative hospital stay were shorter in the laparoscopic group（P〈0.05,respectively）.There was no significantly difference in the number of resected lymph nodes and complication rates between two groups.Conclusion Compared to open surgery,laparoscopic surgery for transverse colon cancer is associated with equivalent survival outcomes and better short-term outcomes including less blood loss and faster bowel recovery.Therefore,laparoscopic surgery is a safety and feasible approach for transverse colon cancer.