如何实现外部宏观系统与芯片微观系统之间的衔接一直是微流控芯片分析领域中一个重要的研究课题。本文结合作者所在研究组的工作及成果,介绍了当前微流控高通量试样引入技术的研究进展。其中分别介绍了基于固定储液池、流通池和取样探针3种模式的微流控芯片系统试样引入系统,以及基于毛细管的微流控高通量试样引入系统。此外,还对该领域研究发展的前景进行了展望。
How to achieve the interfacing between macro world and microchip is still one of the important topics in the research of microfluidic chips. In this paper, the recent progress in high-throughput microfluidic sample introduction techniques is described, mainly based on the work achieved in the authors' group. Various high-throughput microfluidic sample introduction systems in three modes including reservoir, flow-through cell and sampling probe based on microchips or capillaries are described. The developing prospects of high-throughput sample introduction techniques are also forecasted.