中文摘要：

制备了聚（丙烯酰胺-乙二醇二甲基丙烯酸酯）（Poly（AA-EGDMA））整体柱,采用红外（IR）光谱、扫描电子显微镜（SEM）对其结构和形貌进行了表征。基于此,建立了Poly（AA-EGDMA）整体柱毛细管微萃取（CME）-等离子体质谱（ICP-MS）联用检测生物样品中痕量重金属离子的分析方法。对影响CME的诸多条件,如样品溶液的pH值、上样体积、上样流速、解吸剂浓度及体积、解吸剂流速以及共存离子的干扰等进行了详细的考察。在优化的实验条件下,方法对Cd2＋和Pb2＋的检出限分别为4ng·L-1和36ng·L-1,相对标准偏差（c=0.2μg·L-1,n=7）分别为4.7%和3.9%。该整体柱对Cd2＋和Pb2＋的吸附容量分别为46.7μg·m-1和130μg·m-1。将所建立的方法用于尿样中痕量重金属离子Cd2＋、Pb2＋的测定,加标回收率分别为99%和100%。

英文摘要：

Herein,apoly（acrylamide-co-ethylene glycol dimethacrylate）（Poly（AA-EGDMA））monolithic column was prepared by in situ polymerization and characterized by Fourier infrared spectroscopy（FT-IR）and scanning electron microscope（SEM）.Based on it,a method of poly（AA-EGDMA）monolithic column capillary microextraction（CME）-inductively coupled plasma mass spectrometry（ICP-MS）was developed for the determination of trace heavy metal ions in biological samples.Various influencing parameters（such as sample pH,eluent concentration,elution volume,flow rates of eluent and sample solution,sample volume,co-exsiting ions）affecting CME of target analytes were studied in detail.Under the optimal experimental conditions,the detection limits obtained by the proposed method were 4ng·L-1 and36ng·L-1 with the relative standard deviations of 4.7% and 3.9%（c=0.2μg·L-1,n=7）for Cd2＋and Pb2＋,respectively.The adsorption capacities of poly（AA-EGDMA）monolithic column were 46.7μg·m-1 and130μg·m-1 for Cd2＋and Pb2＋,respectively.The proposed method was successfully applied to the analysis of trace Pb2＋and Cd2＋in human urine sample.