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中文摘要：
目的探讨观察贵阳地区部分贵阳地区C,6PD缺乏症的产前筛查及临床应用。方法方便选取2011年1月-2013年12月贵阳地区部分育龄人群G6PD缺乏症筛查女性984例，采用连续监测速率法对入选女性进行G6PD活性定量检测，对于疑似患者采用改良葡萄糖6-磷酸脱氢酶（G6PD）测定试剂盒进行测定，分析贵阳地区部分育龄人群G6PD缺乏症的产前筛查及临床应用情况。结果贵阳地区部分育龄人群G6PD缺乏症筛中2011年确诊阳性率为1．70％，2012年确诊阳性率为3．23％，2013年确诊阳性率为3．70％。984例患者中，最终确诊30例，确诊阳性率为3．05％；确诊的30例G6PD缺乏症患者中出生后16例男婴，14例女婴。男婴G6PD缺乏症发生率，显著高于女婴（P〈0．05）；男婴重度缺乏症发生率，显著低于女婴（P〈0．05）。结论贵阳地区部分育龄人群G6PD缺乏症发生率较高，应加大筛查和宣传力度。做到G6PD缺乏症的早期预防。
英文摘要：
Objective To observe the part Guiyang Guiyang G6PD deficiency of prenatal screening and clinical application. Methods Convenient selection January 2011 to December 2013 Guiyang section of childbearing age G6PD deficiency screening for women 984 cases, the use of continuous monitoring of the rate method selected women with G6PD activity quantitative detection for suspected patients with improved glucose 6 - phosphate removal catalase （G6PD） assay kit was measured, the analysis section of childbearing age G6PD deficiency in Guiyang prenatal screening and clinical application. Results Guiyang section of childbearing age G6PD deficiency screening in 2011 confirmed the positive rate was 1.70%, in 2012, confirmed the positive rate was 3.23%, in 2013 confirmed the positive rate was 3.70%. 984 cases of patients ultimately diagnosed 30 cases confirmed positive rate of 3.05%; diagnosed 30 cases of patients with G6PD deficiency after the baby was born 16 cases, 14 cases of baby girl. Baby G6PD deficiency prevalence was significantly higher than girls（P 〈0.05）; the babysevere deficiency incidence was significantly lower than girls （P 〈0.05）. Conclusion Guiyang section of childbearing age G6PD deficiency higher incidence of disease, should increase screening and propaganda, so that G6PD deficiency early prevention of disease.
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