gliomas 在的背景成功的处理或邻近语言区域组成主要挑战到神经外科。现在的学习被执行评估经由 intraoperative 印射直接外皮的电的刺激在下面的语言的过程当表现在 resective glioma surgery.Methods 以前时,唤醒麻醉有 gliomas 和左半球的优势的三十个病人并且,经历了经由 intraoperative 印射直接外皮的电的刺激在下面的语言在 resective glioma 外科前唤醒麻醉,回顾地被分析。所有病人有肿瘤在或邻近外皮的语言区域。大脑损害与语言功能的区域的保藏根据解剖功能的边界被移开。外科手术前、手术后的功能的调查结果是 evaluated.Results Intraoperative 语言区域在 20 个病人然而并非在四个病人被检测。为对麻醉或到 intracranial 压力的 intraoperative 增加可归因的原因印射失败的语言在在六月后续以后与中等或严重的语言赤字介绍的六个 cases.Seven 病人发生了。全部的切除术在四 cases.Conclusions Intraoperative 外皮的电的刺激在 14 种情况,在 12 种情况中的近总数的切除术和小计切除术中被完成是语言外皮的鉴定的一条精确、安全的途径。唤醒颅骨切开术 intraoperative 外皮的电的刺激,在有 presurgical 的联合识别肿瘤切除术的解剖功能的边界的神经病学的功能的成像,当保存正常语言功能并且最小化手术后的语言赤字的风险时,允许广泛的肿瘤切除。
Background Successful treatment of gliomas in or adjacent to language areas constitutes a major challenge to neurosurgery. The present study was performed to evaluate the procedure of language mapping via intraoperative direct cortical electrical stimulation under awake anaesthesia when performed prior to resective glioma surgery. Methods Thirty patients with gliomas and left-hemisphere dominance and, who underwent language mapping via intraoperative direct cortical electrical stimulation under awake anaesthesia before resective glioma surgery, were analyzed retrospectively. All patients had tumors in or adjacent to cortical language areas. The brain lesions were removed according to anatomic-functional boundaries with preservation of areas of language function. Both preoperative and postoperative functional findings were evaluated. Results Intraoperative language areas were detected in 20 patients but not in four patients. Language mapping failure for reasons attributable to the anaesthesia or to an intraoperative increase in intracranial pressure occurred in six cases. Seven patients presented with moderate or severe language deficits after six months of follow-up. Total resection was achieved in 14 cases, near-total resection in 12 cases and subtotal resection in four cases. Conclusions Intraoperative cortical electrical stimulation is an accurate and safe approach to identification of the language cortex. Awake craniotomy intraoperative cortical electrical stimulation, in combination with presurgical neurological functional imaging to identify the anatomic-functional boundaries of tumor resection, permits extensive tumor excision while preserving normal language function and minimizing the risk of postoperative language deficits.