中文摘要：

有 thrombocytopenia 症候群病毒(SFTSV ) 的严重发烧是 glycoproteins Gn/Gc 的一个稠密的 icosahedral 数组盖住的一个塑造地球的病毒调停到主人房间和病毒、细胞的膜的熔化的病毒的附件。几个膜因素涉及病毒入口，包括 C 类型 lectins 和 nonmuscle 肌浆球蛋白重链 IIA。Gc 蛋白质的熔化以后的水晶结构建议它是班 II 膜熔化蛋白质，类似于 flaviviruses 和 alphaviruses 的 E/E1 蛋白质。病毒粒子通过 clathrin 依赖的小径被使内在化进宿主细胞内涵体，在低 pH 与细胞膜激活病毒的熔化的地方。与从另外的 bunyaviruses 上的研究的信息，此处，我们将考察我们 SFTSV 的入口过程的知识。

英文摘要：

Severe fever with thrombocytopenia syndrome virus （SFTSV） is a globe-shaped virus covered by a dense icosahedral array of glycoproteins Gn/Gc that mediate the attachment of the virus to host cells and the fusion of viral and cellular membranes. Several membrane factors are involved in virus entry, including C-type lectins and nonmuscle myosin heavy chain IIA. The post-fusion crystal structure of the Gc protein suggests that it is a class II membrane fusion protein, similar to the E/E1 protein of flaviviruses and alphaviruses. The virus particles are internalized into host cell endosomes through the clathrin-dependent pathway, where the low pH activates the fusion of the virus with the cell membrane. With information from studies on other bunyaviruses, herein we will review our knowledge of the entry process of SFTSV.