目的探讨输尿管移行细胞癌术后膀胱复发的危险因素。方法选择2003年1月—2007年6月我院收治的行手术治疗的输尿管移行细胞癌患者60例,回顾性分析其病历资料,根据术后随访结果将患者分为未复发组41例,复发组19例。结果输尿管移行细胞癌术后膀胱复发率为31.7%(19/60)。单因素分析结果显示,两组患者的淋巴转移阳性率、肿瘤分级、肿瘤数量、合并膀胱肿瘤发生率、尿脱落细胞阳性率比较,差异均有统计学意义(P〈0.05)。多因素非条件Logistic回归分析结果显示,淋巴转移阳性、肿瘤分级3级、合并膀胱肿瘤及尿脱落细胞阳性对回归方程的影响有统计学意义(P〈0.05)。结论输尿管移行细胞癌发病率低,但术后膀胱复发率较高,淋巴转移阳性、肿瘤分级3级、合并膀胱肿瘤及尿脱落细胞阳性是术后膀胱复发的独立危险因素。
Objective To investigate the risk factors of postoperative intravesical recurrence of transitional cell carcinoma of the ureter.Methods Among the 60 patients with transitional cell carcinoma of the ureter,admitted to our hospital from January 2003 to June 2007,there were 19 patients with intravesical recurrence and 41 patients without intravesical recurrence,clinical features were compared between the 2 groups.Results In univariate analysis,statistic significance was found in lymph node metastasis positive rate,tumor grade,tumor number,complicated with bladder tumor incidence,urine exfoliated cells positive rate between the two groups(P《0.05).Multivariate analyses indicated that lymph node metastasis positive,tumor grade 3,complicated with bladder tumor incidence,and urine exfoliated cells positive were associated with intravesical recurrence(P《0.05).Conclusion Lymph node metastasis positive,tumor grade 3,complicated with bladder tumor incidence,and urine exfoliated cells positive are the risk factors which independently associated with intravesical recurrence of transitional cell carcinoma of the ureter.