中文摘要：

以带正电的几丁聚醣（CS）与带负电的三聚磷酸钠（TPP）通过离子交联作用包覆分离大豆蛋白质水解物（ISPH）制成CS—ISPH—TPP亚微米颗粒，利用动态光散射法分析ISPH浓度、CS分子量及CS／TPP质量比对亚微米颗粒的粒径与表面电位的影响。结果表明，CS-ISPH-TPP亚微米颗粒的粒径随ISPH添加浓度的增加而增大，而表面电位则无明显变化。CS—TPP与CS-ISPH—TPP亚微米颗粒的粒径会随CS分子量的增加而增大，且包覆ISPH颗粒的粒径均大于未包覆的颗粒，而表面电位则介于41．9～44．2mV之间。CS／TPP质量比由6：1减至4：1时，颗粒粒径会随之增加，而由4：1减至2：1时，粒径则变小；CS／TPP质量比由6：1减至3：1时，颗粒表面均带有高度的正电荷，继续减至2：1时，表面电位会出现骤降的情形。

英文摘要：

CS-ISPH-TPP nanoparticles were prepared by isolated soy protein hydrolysate being coated through ionic crosslinking between chitosan hydrolysate（CS） with negative charge and sodium tripolyphosphate （TPP） with positive charge. The effects of ISPH concentration, chitosan molecular weight and CS/TPP mass ratio on the size and zeta potential of these nanoparticles were investigated by dynamic light scattering method. The results showed that, the size of CS-ISPH-TPP nanoparticles increased with ISPH concentration increasing and there was no obvious change in zeta potential. The size of CS-TPP and CS-ISPH-TPP nanoparticles increased with chitosan molecular weight increasing and zeta potential lied during 41.9 -44.2 mV. The size of CS-TPP and CS-ISPH-TPP nanoparticles increased for CS/TPP mass ratio decreasing from 6 ： 1 to 4 ： 1 and decreased for CS/TPP mass ratio decreasing from 4 ： 1 to 2 ： 1. The surface of CS-TPP and CS-ISPH-TPP nanoparticles possessed a high degree of positive charge for CS/TPP mass ratio decreasing from 6 ： 1 to 4 ： 1 and the zeta potential decreased rapidly for CS/TPP mass ratio decreasing from 4 ： 1 to 2 ： 1.