欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
在单分子水平研究聚合物体系的分子内及分子间相互作用,对于揭示其结构-性能的关系,进而实现对相应功能的调控极为重要.基于原子力显微镜技术（AFM）的单分子力谱,由于其操作简单且适用面广,在单分子研究领域得到了广泛的应用.本文概括了该技术在生物高分子及合成高分子体系的研究进展.对于生物高分子体系,主要介绍了核酸（DNA/RNA）、蛋白质和多糖（淀粉）的单分子力谱研究及利用各自力学指纹谱对其它分子间的相互作用的研究.对于合成高分子体系,主要介绍了聚合物的一级结构与单链弹性的关系及溶剂和聚集态结构等对高分子单链力学性质的影响规律.
英文摘要：
The investigations on inter- or intra-molecular interactions in polymer systems at the single-molecule level are of pivotal importance in revealing the relationship between structure and function and eventually getting good controls on the corresponding function.Atomic force microscopy（AFM）-based single-molecule force spectroscopy（SMFS） has been used widely in the field of single-molecule study due to its friendly user interface（i.e.,easy to use and can work in both aqueous solution and organic solvents） and world-wide commercialization.In this article,we introduced recent advancements in AFM-based single-molecule force spectroscopy study of polymer（including biopolymer and synthetic polymer） interactions.For biopolymer system,we first introduced typical force fingerprints of nucleic acid,protein and polysaccharides,and then discussed the force-fingerprint-based investigation of molecular interactions.For synthetic polymer system,the relationship between primary structure and single chain elasticity was discussed first,and then the effects of both single chain aggregates and the bulk aggregates on the elasticity of polymer chains were discussed.
同期刊论文项目
同项目期刊论文
Hierarchical Self-Assembly of Surfactant-Encapsulated and Organically Grafted Polyoxometalate Comple
Preparation, Structure, and Imaging of Luminescent SiO2 Nanoparticles by Covalently Grafting Surfact
Drying and Nondrying Layer-by-Layer Assembly for the Fabrication of Sodium Silicate/TiO(2) Nanoparti
Embedding graphene nanoparticles into poly(N,N ';-dimethylacrylamine) to prepare transparent nanocom
A supramolecular gel based on an adenine symmetrically grafted Anderson-type polyoxometalate complex
Luminescent Dendrimers Composed of Quinacridone Core and Carbazole Dendrons: Structure, Electrochemi
Synthesis and redox-responsive self-assembly of ferrocene grafted Anderson-type polyoxometalate hybr
A green emissive amorphous fac-Alq(3) solid generated by grinding crystalline blue fac-Alq(3) powder
Self-assembly and supramolecular liquid crystals based on organic cation encapsulated polyoxometalat
Synthesis and characterizations of novel spindle-like terphenyl-type chromophores for non-linear opt
Nucleation of Aqueous Semiconductor Nanocrystals: A Neglected Factor for Determining the Photolumine
Bioinspired Water-Vapor-Responsive Organic/Inorganic Hybrid One-Dimensional Photonic Crystals with T
Coomassie Brilliant Dyes as Surface-Enhanced Raman Scattering Probes for Protein-Ligand Recognitions
Exponential growth of layer-by-layer assembled coatings with well-dispersed ultrafine nanofillers: a
Stable water-dispersed organic nanoparticles: preparation, optical properties, and cell imaging appl
Sensing of polycyclic aromatic hydrocarbons with cyclodextrin inclusion complexes on silver nanopart
A pluronic F127 coating strategy to produce stable up-conversion NaYF4:Yb,Er(Tm) nanoparticles in cu
Achieving high open-circuit voltage in the PPV-CdHgTe bilayer photovoltaic devices on the basis of t
Correlation between Annealing-Induced Growth of Nanocrystals and the Performance of Polymer: Nanocry
Theoretical study on the charge transport property of Pt((CNBu)-Bu-t)(2)(CN)(2) nanowires induced by
A Twisting Donor-Acceptor Molecule with an Intercrossed Excited State for Highly Efficient, Deep-Blu
Instantaneous and reversible gelation of organically grafted polyoxometalate complexes with dicarbox
Construction of nanoparticle superstructures on the basis of host-guest interaction to achieve perfo
Avoiding coffee ring structure based on hydrophobic silicon pillar arrays during single-drop evapora
Photo-Responsive Self-Assembly of an Azobenzene-Ended Surfactant-Encapsulated Polyoxometalate Comple
Surface Chemistry Routes to Modulate the Photoluminescence of Graphene Quantum Dots: From Fluorescen
Patterning Organic/Inorganic Hybrid Bragg Stacks by Integrating One-Dimensional Photonic Crystals an
Interfacial Charge-Transfer Effects in Semiconductor-Molecule-Metal Structures: Influence of Contact
Elevated Ag nanohole arrays for high performance plasmonic sensors based on extraordinary optical tr
EMSA and Single-Molecule Force Spectroscopy Study of Interactions between Bacillus subtilis Single-S
The Nature of the Force-induced Conformation Transition of dsDNA Studied by Using Single Molecule Fo
Study On Intercalations Between Double-Stranded DNA And Pyrene By Single-Molecule Force Spectroscopy
Single-molecule Study on Intermolecular Interaction between C60 and Porphyrin Derivatives: Toward Un
Full View of Single-molecule Force Spectroscopy of Polyaniline in Oxidized, Reduced and Doped States
期刊信息
位置：