中文摘要：

在新型近β医用钛合金Ti-3Zr-2Sn-3Mo-25Nb（TLM）表面用微弧氧化法制备一层多孔薄膜,利用XRD、SEM、EDS考察了微弧氧化膜的晶相组成、表面微观形貌和元素特征,并通过体外模拟体液（SBF）浸泡和成骨细胞培养试验研究该微弧氧化膜的骨诱导活性。结果表明,TLM合金表面的微弧氧化薄膜主要由金红石型和锐钛矿型TiO2组成,金红石型TiO2所占比例较大。该微弧氧化膜是一种含钙磷元素、多孔、具有陶瓷特性的混合物,微孔布满整个膜层,且在内部相互交联相通,微弧氧化薄膜与TLM基体间的结合强度为43 MPa。该微弧氧化薄膜在模拟体液中可诱导生成活性羟基磷灰石,磷灰石沉积层与微弧氧化薄膜间的结合强度为31 MPa。细胞培养结果显示,成骨细胞能够在微弧氧化膜表面很好地黏附和生长。

英文摘要：

A porous film on the surface of novel near β biomedical titanium alloy TLM （Ti-3Zr-2Sn-3Mo-25Nb）was prepared by micro-arc oxidation method. The phase composition, surface micro-topography and element characteristics of the micro-arc oxidation films was investigated with XRD, SEM and EDS, and the osteoinduction of micro-arc oxidation films was tested by simulated body fluid （SBF） test and osteoblasts cultivation test in vitro. The results show that the micro-arc oxidation films are mainly composed ofanatase and rutile type TiO2, the futile TiO2 has high content. The micro-arc oxidationis a kind of ceramic intermixture of porous and contains Ca and P elements, the microholes are distributed on the whole films and communicated, and the interfacial bonding strength between micro-arc oxidation films and TLM substrate is 43 MPa. The films in SBF can induce apatite formation with the excellent bioactivity, and the inteIfacial bonding strength between micro-arc oxidation films and bone-like apatite coating is 31 MPa. The cell test indicates that osteoblasts can grow well on the surface of micro-arc oxidation films.