位置:成果数据库 > 期刊 > 期刊详情页
平胃散调控湿困脾胃证大鼠肠道能量代谢的实验研究
  • ISSN号:1671-0258
  • 期刊名称:山西中医学院学报
  • 时间:0
  • 页码:27-29
  • 分类:R285[医药卫生—中药学;医药卫生—中医学]
  • 作者机构:[1]成都中医药大学基础医学院,四川成郡611137
  • 相关基金:国家自然基金资助项目(30973713)
  • 相关项目:平胃散调控湿阻中焦证致水通道蛋白异常表达的机制研究
中文摘要:

目的:探究平胃散对湿困脾胃证大鼠肠道能量代谢障碍的调节作用。方法:40只SD大鼠分为空白组、模型组、平胃散组和自然恢复组。除空白组外,其余各组大鼠均造模,给药3 d后,处死大鼠,检测大鼠空肠Gln含量以及Na+-K+-ATPase、Ga2+-ATPase活力。结果:与模型组比较,平胃散组Gln含量升高,差异有统计学意义(P〈0.01);Na+-K+-ATPase、Ga2+-ATPase活力升高,差异无统计学意义。结论:湿困脾胃证大鼠肠黏膜能量代谢出现障碍,平胃散有调节作用。

英文摘要:

Objective:To study regulation effect of Pingwei powder on energy metabolism disorder of intestinal tract ot rats with syndrome of dampness blocking spleen and stomach. Methods:40 rats were randomly divided into blank group,model group,Pingwei power group and natural recovery group.In addition to blank group,rats in other groups were constructed models with dampness blocking spleen and stomach. 3 d after administration, rats were sacrificed,then Gln content and Na~- K+-ATPase,Ga2~-ATPase activity in jejunum of rats were detected. Results:Compared with model group,Gin content was significantly increased in Pingwei powder group (P〈0.01);Na-K+-ATPase,Ga2+-ATPase activity were increased in Pingwei powder group,but there was no statistically difference. Cortclusions:Pingwei powder could regulate energy metabolism disorder of intestinal mucosa of rats with syndrome of dampness blocking spleen and stomach.

同期刊论文项目
同项目期刊论文
期刊信息
  • 《山西中医学院学报》
  • 主管单位:山西省卫生和计划生育委员会
  • 主办单位:山西中医学院
  • 主编:李青山
  • 地址:山西省晋中市榆次区高校园区大学街121号
  • 邮编:030619
  • 邮箱:sxzyxyxb@126.com
  • 电话:0351-3179828
  • 国际标准刊号:ISSN:1671-0258
  • 国内统一刊号:ISSN:14-1265/R
  • 邮发代号:22-71
  • 获奖情况:
  • 山西省一级期刊
  • 国内外数据库收录:
  • 被引量:6131