中文摘要：

在制备复合磷酸盐多孔陶瓷的基础上，采用稀浆料对其进行多次重复涂覆，通过扫描电镜（SEM）、排水法和体外细胞实验等对比了多次涂覆前后样品的孔隙特征，表面结构和细胞相容性。结果发现，随着涂覆次数的增加，样品的孔壁厚度有所增加，孔隙率呈下降趋势。不过经过3次涂覆后，样品孔隙形貌并没有太大的变化，孔隙率仍大于80％。同时多次涂覆使陶瓷表面增加了大量的1～2μm的微孔结构，体外实验结果显示，这种结构有利于兔骨髓基质干细胞的粘附、铺展和生长。研究表明，多次涂覆（特别是3次涂覆）在不明显改变多孔陶瓷孔隙特征的前提下，改变了表面微观结构，提高了细胞相容性。

英文摘要：

Polyphosphate porous ceramics were prepared and then recoated with thinner slurry. Macroporous characteris- tics, surface topology and cytocompatibility of samples before and after being recoated was evaluated using scan emission microscope （SEM）, the Archimedes drainage method and the cells cultivation test in vitro. The results show that the pore wall thickness of samples increases with the increase of coating times, which slighty decreases their porosity. After being coated for 3 times, however, the macroporous morphology does not change obviously and the porosity is still more than 80%. Simultaneously, plenty of micropores with about 1-2 ~rn diameter are observed on the wall surfaces of samples. Furthermore, these surfaces are in favor of rabbit bone mesenchymal stem cells （RBMSC） adhesion, spreading and pro- liferation. These results indicate that the recoating process, especially repeated for 3 times, alters the surface topology of samples and enhances their cytocompatibility, but not sacrifices their macroporous characteristics.