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神经营养因子对喉返神经损伤再生的研究进展
  • ISSN号:1671-2420
  • 期刊名称:《中国眼耳鼻喉科杂志》
  • 时间:0
  • 分类:R739.91[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]上海交通大学附属第一人民医院耳鼻咽喉头颈外科,上海200080
  • 相关基金:国家自然科学基金(81271067/H1302)
中文摘要:

目的探讨颈部神经鞘瘤的诊断、治疗及预后特点,以提高对其临床诊疗的认识。方法对46例颈部神经鞘瘤的临床资料进行回顾性研究。结果临床症状体征、辅助检查(B超、CT、MRI)以及细针穿刺抽吸活检有助于该病的诊断,确诊依靠术后病理诊断。在已确定神经来源的病例中,该肿瘤臂丛神经源性最常见。46例均接受手术治疗,在随访期限内均无复发。除了14例术前存在神经症状及2例术中切断相关神经的患者外,其他病例无明显神经损伤后遗症。结论手术切除是治疗颈部神经鞘瘤的有效方法。神经鞘瘤虽为良性,但应根据肿瘤的大小、部位、临床表现及患者的需求选择合适的手术方法,尽可能地保护相关神经的完整性。

英文摘要:

Objective To improve the diagnosis and surgical treatment of cervical neuriemmona. Method The clinical data of 46 patients with schwannoma of head and neck from January 2003 to December 2012 were reviewed. Results Clinical symptoms and signs,auxiliary examination( e. g. ultrasound imaging,CT,MRI) and Fine Needle Aspiration Cytology( FNAC) might be useful in the diagnosis of schwannomas,while the postoperative histopathologic examination was the gold standard. The origin of tumors were nerves,in which brachial plexus was the most common. All the patients undertook the surgery. During the follow-up,there was no recurrence. All of them showed no evident neurological sequelae except for the 14 patients who presented neurological symptoms before the operation and the other 2 patients whose nerves of origin were sacrificed. Conclusion Tumor resection is still the most effective treatment available for patients with schwannomas. Although the tumour is benign,surgeons should choose the appropriate approaches to maintain the integrity of nerve based on the tumour's size,location,clinical symptoms and signs,and the patients' desire.

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期刊信息
  • 《中国眼耳鼻喉科杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国教育部
  • 主办单位:复旦大学附属眼耳鼻喉科医院
  • 主编:王正敏 孙兴怀
  • 地址:上海市汾阳路83号(复旦大学附属眼耳鼻喉科医院内)
  • 邮编:200031
  • 邮箱:eentm@sina.com
  • 电话:021-64376491
  • 国际标准刊号:ISSN:1671-2420
  • 国内统一刊号:ISSN:31-1875/R
  • 邮发代号:4-705
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:5225