目的探讨院前硝酸甘油急救对心肌梗死心电图结果的影响。方法应用随机数字表法将2008年6月~2012年6月在我院急诊科住院治疗的96例急性心肌梗死患者分为对照组和实验组,对照组给予尿激酶静脉溶栓治疗.实验组则硝酸甘油静脉滴注进行治疗,两组其他治疗措施相同,观察对照组和实验组患者心电图结果的变化、临床治疗效果和并发症发生情况。结果实验组和对照组临床疗效、出院前死亡、梗死后心绞痛和心力衰竭或者休克方面差异无统计学意义(P〉0.05),但是实验组患者在心律失常和出血发生率方面明显低于对照组的(P〈0.05)。结论硝酸甘油治疗急性心肌梗死疗效确切,安全可靠,主要终点事件发生率低,不良反应发生少,明显改善患者的心电图结果,值得进一步推广使用。
Objective To investigate influence of electrocardiogram results on patients with acute myocardial infarction by nitroglycerin before the court. Methods The clinical data of ninety-six patients with acute myocardial infarction who were treated in the emergency department from June 2008 to June 2012 were collected,then patients were divided into the control group and observation group by using a random number table. Patients in the control group was given nitroglycerin intravenous drip,but patients in the observation group was given urokinase intravenous thrombolysis, the change of electrocardiogram results. The clinical efficacy and complications of patients with acute myocardial infarction in the control group and the observation group were evaluated. Results The total efficient rate, the death rate before discharge, infarction angina pectoris rate and heart failure or shock rate were not different(P 〉 0.05), but arrhythmia rate and bleeding incidence were lower in the observation group than in the control group (P 〈 0.05). Conclusion Nitroglycerin can obtained satisfactory curative effect for patients with acute myocardial infarction, it is safe, reliable, low primary end point event rates and ad- verse reactions rate. It is worthy of clinical application.