通过将月桂胺(DA)与环氧氯丙烷发生开环反应所得的氯醇分子进一步在KOHHz0溶液中进行闭环反应,制备得到具有良好反应活性的表面活性剂中间体N,N-二-2,3环氧丙基月桂胺(EDA)。采用FTIR,^1H—NMR,^13C—NMR等表征手段对产物的结构进行了表征。研究了闭环反应温度、碱的用量、环氧氯丙烷的用量、碱的种类和闭环反应时间等反应条件对产物中EDA含量的影响,在此基础上确定了N,N-二-2,3-环氧丙基月桂胺的最优化反应条件。
N, N-di-2,3-epoxypropyl dodecylamine (EDA), an important intermediate of the surfactants with good chemical reactivities, was synthesized via ring-closing reaction of the chlorohydrin, which was prepared through the ring-opening reaction of the epichlorohydrin with dodecylamine, in the KOH-H2O solutions. The structure of the products were characterized through FTIR, ^1H-NMR and ^13C-NMR spectrum. Influence of the reaction conditions, such as temperature and time of the ring- closing reaction, amount of the alkali and epichlorohydrin, types of the alkali, etc. on the content of EDA in the produces were studied, and then the optimal conditions for synthesizing N, N-di-2,3-ep- oxypropyl dodecylamine was defined.