中文摘要：

衰变加速因子为体内补体调控蛋白家族中的一种重要的同源限制因子,它对于防止同源补体对自身组织细胞的溶破有重要意义,并参与机体多种病理生理过程,如肿瘤免疫、生殖免疫、微生物感染等。本文综述了DAF的结构及其功能研究进展,并指出了其在免疫学,尤其在异种器官移植方面的应用前景及存在的问题。

英文摘要：

Decay Accelerating Factor(DAF), an important homologous inhibitor, belongs to the regulators of complement activation (RCA) . It plays an important role in preventing complement-mediated autologous tissue damage . Moreover, it participates in many processes, such as tumor immunity, reproductive immunity and infection of microorganism. Recent advances on structure and function are introduced comprehensively. Also its prospects and expanding questions of application in immunology, especially in the field of x...